【Beijing】Preparation and Evaluation of Polysaccharide Conjugate Vaccine

Using the 2022 Nobel Prize technique of "Click chemistry" to covalently bind polysaccharide conjugation to carrier proteins with adjuvant T-cell antigenic epitopes, this polysaccharide-conjugated vaccine will greatly improve the immunological properties of the polysaccharide and provide effective protection for infants and children.

The program invites experts in vaccine development from national research institutesto take students into the front-line key laboratories to learn the basics of polysaccharide-conjugated vaccine preparation, characterization and evaluation, and to operate advanced laboratory equipment.

I mastered the practical operation of various laboratory instruments, which I had only seen in textbooks. What impressed me the most was using the pipette to dilute serum. Each time before pushing the pipette, it was crucial to stay focused and think quickly to avoid mistakes. Our group nearly had to start over in this experiment due to an error, but we didn't get discouraged and finally found a way to fix it.
Through this program, I confirmed the professional direction I want to pursue and strengthened my resolve to delve deeper into this field. I hope that in the future, I can lead my country and all of humanity toward a brighter future.
—— Zhengzhou No. 1&8 United International School, Student Li
My main takeaway from this program is the laboratory experiments, which are the most valuable and far more efficient than other components. Here, I could broaden my horizons, understand the operational processes of professional laboratories, and use specialized equipment for professional experiments. Moreover, this program focused on a fascinating topic, so laboratory work is my favorite aspect of the program.
—— Shanghai High School International Division(High School), Student Ding
This program combined theory with practice, allowing us to explore new horizons in chemistry and encounter more novel concepts. The experiments reinforced our textbook knowledge and enhanced our practical skills and ability to link theory with practice. The hands-on experience during the experiments deepened our understanding and application of the concepts.
The experiment on Type I Pneumococcal Polysaccharide Capsule Oxidation gave me the most significant rewards, including valuable experience and skills in laboratory procedures, friendships, and a deeper understanding of the importance of teamwork that enabled us to accomplish tasks better, share information and resources, and learn from each other, thereby improving overall work efficiency and quality.
——Chengdu Foreign Languages School, Student Liu